Super-resolution microscopy overcomes the diffraction limit of light and allows investigators to study subcellular structures in greater detail than is possible with a confocal microscope. Resolutions down to 20 nm are possible; in biology this represents the length of 10 average proteins end to end or 60 base pairs of DNA. With the introduction of the very first super-resolution microscope in 2004, and now our Leica TCS SP8 STED 3X and Leica SR GSD 3D, Leica Microsystems revolutionized opportunities for life science research allowing novel discoveries to be made in the fields of virology, neuroscience and cancer. True to the credo of Ernst Leitz ‘with the user, for the user’, Leica Microsystems has pioneered super-resolution by collaborating closely with leading scientists such as the Nobel Prize laureate Stefan Hell, as well as industry partners. This approach continuously improves the performance of our super-resolution microscopy systems. With 10 years of experience in the field, today we offer more than excellent products: Our commitment to high standards of service and support is also a key priority for Leica Microsystems.